FRAGMIN 9 Drug Interactions

dalteparin sodium

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9.2 Drug Interactions Overview

The drug interactions overview is not available.

9.3 Drug-Behavioural Interactions

Interactions with individual behaviours have not been established.

9.4 Drug-Drug Interactions

Fragmin should be used with caution in patients receiving oral anticoagulants, platelet inhibitors, non-steroidal anti-inflammatories, thrombolytic agents and dextran because of increased risk of bleeding. Acetylsalicylic acid (ASA), unless contraindicated, is recommended in patients treated for unstable angina or non-Q-wave myocardial infarctions (see 4 DOSAGE AND ADMINISTRATION, 8 ADVERSE REACTIONS).

Because NSAIDs and ASA analgesic/anti-inflammatory doses reduce production of vasodilatory prostaglandins, and thereby renal blood flow and renal excretion, particular care should be taken when administering dalteparin concomitantly with NSAIDs or high dose ASA in patients with renal failure.

9.5 Drug-Food Interactions

Interactions with food have not been established.

9.6 Drug-Herb Interactions

Interactions with herbs have not been established.

9.7 Drug-Laboratory Test Interactions

Interactions with lab tests have not been established

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9 Drug Interactions

9.2 Drug Interactions Overview

The drug interactions overview is not available.

9.3 Drug-Behavioural Interactions

Interactions with individual behaviours have not been established.

9.4 Drug-Drug Interactions

Fragmin should be used with caution in patients receiving oral anticoagulants, platelet inhibitors, non-steroidal anti-inflammatories, thrombolytic agents and dextran because of increased risk of bleeding. Acetylsalicylic acid (ASA), unless contraindicated, is recommended in patients treated for unstable angina or non-Q-wave myocardial infarctions (see 4 DOSAGE AND ADMINISTRATION, 8 ADVERSE REACTIONS).

Because NSAIDs and ASA analgesic/anti-inflammatory doses reduce production of vasodilatory prostaglandins, and thereby renal blood flow and renal excretion, particular care should be taken when administering dalteparin concomitantly with NSAIDs or high dose ASA in patients with renal failure.

9.5 Drug-Food Interactions

Interactions with food have not been established.

9.6 Drug-Herb Interactions

Interactions with herbs have not been established.

9.7 Drug-Laboratory Test Interactions

Interactions with lab tests have not been established

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