The Talzenna Product Monograph is available here
HRR gene-mutated Metastatic Castration-Resistant Prostate Cancer (mCRPC)
TALZENNA is indicated in combination with enzalutamide for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC).
Breast Cancer Susceptibility Gene (BRCA)-mutated (gBRCAm) Human Epidermal Growth Factor Receptor 2 (HER2)-negative Locally Advanced or Metastatic Breast Cancer
TALZENNA (talazoparib) is indicated as a monotherapy for the treatment of adult patients with a deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated human epidermal growth factor receptor 2 (HER2)-negative locally advanced (not amenable to curative radiation or surgery) or metastatic breast cancer, who have previously been treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting, unless patients were inappropriate for these treatments.
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