XELJANZ / XELJANZ XR (tofacitinib) 2 Contraindications

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XELJANZ/XELJANZ XR (tofacitinib) is contraindicated:

  • In patients with known hypersensitivity to tofacitinib or ingredient in the formulation, including any non-medicinal ingredient, or component of the container. For a complete listing, see 6 DOSAGE FORMS, STRENGTHS, COMPOSITION AND PACKAGING.
  • In patients with severe hepatic impairment (see 7 WARNINGS AND PRECAUTIONS).
  • During pregnancy and breastfeeding (see 1.1 Pregnancy and 7.1.2 Breast-feeding).