XALACOM (latanoprost and timolol maleate) is contraindicated in patients with:
- reactive airway disease including bronchial asthma, a history of bronchial asthma, or severe chronic obstructive pulmonary disease.
- sinus bradycardia, sick sinus syndrome, sino-atrial block, second or third degree atrioventricular block not controlled with pace-maker, overt cardiac failure, or cardiogenic shock.
- known hypersensitivity to latanoprost, timolol, benzalkonium chloride or any other ingredient in the product. For a complete listing, see the DOSAGE FORMS, COMPOSITION and PACKAGING section of the product monograph.