SODIUM BICARBONATE INJECTION USP (sodium bicarbonate injection USP) Symptoms And Treatment Of Overdosage

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Should alkalosis result, the bicarbonate should be stopped and the patient managed according to the degree of alkalosis pre­sent. A 0.9% sodium chloride intravenous injection may be given; potassium chloride may also be indicated if there is hypokalemia.  Severe alkalosis may be accompanied by hyper­irritability or tetany and these symptoms may be controlled by calcium gluconate. An acidifying agent such as ammonium chloride may also be indicated in severe alkalosis (see WARNINGS and PRECAUTIONS).