LORBRENA (lorlatinib) 3 Serious Warnings And Precautions Box

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Serious Warnings and Precautions

  • Hypercholesterolemia / Hypertriglyceridemia (see 7 WARNINGS AND PRECAUTIONS, Metabolism and Endocrine, Hyperlipidemia)
  • Pneumonitis (see 7 WARNINGS AND PRECAUTIONS, Respiratory, ILD/Pneumonitis)
  • Hepatotoxicity (see 7 WARNINGS AND PRECAUTIONS, General, Drug-Drug Interactions, Risk of Serious Hepatotoxicity with Concomitant Use of Strong CYP3A Inducers)

LORBRENA should only be prescribed and supervised by a qualified physician experienced in the use of antineoplastic agents.