IBRANCE

(palbociclib)

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IBRANCE Quick Finder

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IBRANCE Quick Finder

The Ibrance Product Monograph is available here.

IBRANCE (palbociclib) is indicated for:

  • the treatment of pre/perimenopausal or postmenopausal women, or men with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer in combination with:
    • an aromatase inhibitor as initial endocrine-based therapy; or
    • fulvestrant in patients with disease progression after prior endocrine therapy.

Pre/perimenopausal women and men treated with the combination IBRANCE plus aromatase inhibitor therapy, and pre/perimenopausal women treated with the combination IBRANCE plus fulvestrant therapy should also be treated with a luteinizing hormone releasing hormone (LHRH) agonist.

Clinical effectiveness of IBRANCE in combination with an aromatase inhibitor is based on the benefit observed in patients treated with IBRANCE in combination with letrozole for the treatment of postmenopausal women with advanced breast cancer.

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