Prior to initiating DEPO-TESTOSTERONE (testosterone cypionate injection), the diagnosis of hypogonadism should be confirmed by ensuring that serum testosterone concentrations have been measured in the morning on at least two separate days and that these serum testosterone concentrations are below the normal range. Testosterone levels should then be monitored on a regular basis to ensure adequate response to treatment (See Monitoring and Laboratory Tests). DEPO-TESTOSTERONE should be used only in patients available for re-evaluation at periodic intervals.
DEPO-TESTOSTERONE is to be administered by a health care professional only.
DEPO-TESTOSTERONE is for intramuscular use only and should not be given intravenously. Intramuscular injections should be given deep in the gluteal muscle.
Dosage should be adjusted according to the patient's response and appearance of adverse reactions.
Recommended Dose and Dosage Adjustment
For replacement in the hypogonadal male, 200 mg should be administered every two weeks.
Maximum Dose: 400 mg per month.
If a dose of this medication has been missed, it should be taken as soon as possible. However, if it is almost time for the next dose, skip the missed dose and go back to the regular dosing schedule. Do not double doses.
Parenteral drug products, such as DEPO-TESTOSTERONE, should be inspected visually for particulate matter and discolouration prior to administration. Warming and shaking the vial should redissolve any crystals that may have formed during storage.