Overdosage may result in a period of amenorrhea of a variable length and may be followed by irregular menses for several cycles. Very high doses of DEPO-PROVERA (500 mg daily or more) have been associated with corticoid-like activity and with Cushingoid symptoms (e.g. moon face and blood pressure elevation). There is no known therapy for overdosage.
For management of a suspected drug overdose, contact your regional poison control centre.