DEPO-PROVERA (medroxyprogesterone acetate injectable suspension, USP) 5 Overdosage

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Overdosage may result in a period of amenorrhea of a variable length and may be followed by irregular menses for several cycles.  Very high doses of DEPO-PROVERA (500 mg daily or more) have been associated with corticoid-like activity and with Cushingoid symptoms (e.g. moon face and blood pressure elevation).  There is no known therapy for overdosage. 

For management of a suspected drug overdose, contact your regional poison control centre.