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CHAMPIX (varenicline tartrate) Overdosage

Overdosage

Symptoms

Consistent with its pharmacological profile, CHAMPIX resulted in increased incidences of nausea and vomiting when given at doses greater than the recommended dose of 1 mg BID.

Treatment

Varenicline has been shown to be dialyzed in patients with end-stage renal disease (see ACTION AND CLINICAL PHARMACOLOGY, Special Populations and Conditions: Renal Insufficiency), however, there is no experience with dialysis following overdose.

For management of a suspected drug overdose, contact your regional Poison Control Centre.

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