ALDACTONE (Spironolactone Tablets, USP) Contraindications

Medical Information
Canada
 

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ALDACTONE is contraindicated in:

  • Patients who are hypersensitive to spironolactone, or to any ingredient in the formulation.
  • For a complete listing, see the Dosage Forms, Composition and Packaging Section.
  • Patients with anuria
  • Patients with Addison’s disease
  • Patients with acute renal insufficiency or with severe impairment of renal function (GFR < 30 mL/Min/1.73 m2
  • Patients with hyperkalemia
  • Women who are pregnant
  • Nursing women (see WARNINGS AND PRECAUTIONS, Special Populations, Nursing Women)
  • Combination with eplerenone ( see Warnings and Precautions- Hyperkalemia, Drug Interactions sections)

  • Combination with heparin, low molecular weight heparin ( see Warnings and Precautions- Hyperkalemia, Drug Interactions sections)